This paper uses conditional quantile regression to analyze the effects of genetically modified (GM) seed technology and management on production risk in agriculture, with an application to the distribution of corn yield in Wisconsin.Using the certainty equivalent (CE) as a welfare measure, our analysis decomposes the welfare effects of risk, manage
Cerebellar nuclei neurons show only small excitatory responses to optogenetic olivary stimulation in transgenic mice: in vivo and in vitro studies
To study the olivary input to the cerebellar nuclei (CN) we used optogenetic stimulation in transgenic mice expressing channelrhodopsin-2 (ChR2) in olivary neurons.We obtained Saw Blades in vivo extracellular Purkinje cell (PC) and CN recordings in anesthetized mice while stimulating the contralateral inferior olive (IO) with a blue laser (single p
Assessment of hand hygiene levels among health care settings of a coastal city in Andhra Pradesh
Background: it is known that hand hygiene practice among medical and paramedical play an important role in preventing the transmission of infections.Magnitude of Health Care Associated Infection is very high in developing countries like India due to the numerous factors like under staffing, poor hygiene, lack of basic equipment, inadequate structur
Hepatoprotective effect of Opuntia dillenii seed oil on CCl4 induced acute liver damage in rat
Objective: To investigate the hepatoprotective effect of Opuntia dillenii seed oil (ODSO) on CCl4 provoked liver injury in rat.Methods: Animals were treated orally with ODSO at a concentration of 2 mL/kg, once daily Solid Ink for one week before the first intraperitoneal injection of CCl4, and thereafter the administration of the oil was continued
Increased interactions and engulfment of dendrites by microglia precede Purkinje cell degeneration in a mouse model of Niemann Pick Type-C
Abstract Niemann Hand Mixer Pick Type-C disease (NPC) is an inherited lysosomal storage disease (LSD) caused by pathogenic variants in the Npc1 or Npc2 genes that lead to the accumulation of cholesterol and lipids in lysosomes.NPC1 deficiency causes neurodegeneration, dementia and early death.Cerebellar Purkinje cells (PCs) are particularly hyperse